血浆铜蓝蛋白来自人血清

物理性质

性状：生理盐水。
溶解性：溶于水

作用与用途

Analysis Note Protein determined by biuret
Biochem/physiol Actions Ceruloplasmin (Cp), the principal carrier of copper in plasma, is thought to be involved in oxidative modification of lipoproteins and participate in the acute phase reaction to stress. Cp is an effective antioxidant for a variety of radicals and has a potent peroxidase activity to decompose hydrogen peroxide in the presence of reduced glutathione. It inhibits the peroxidase activity of myeloperoxidase in a concentration-dependent manner and shows selective binding to myeloperoxidase in vitro. This suggests that ceruloplasmin may participate in the clearance and inactivation of myeloperoxidase in vivo. At physiological (micromolar) concentrations it was found to inhibit relaxation of rabbit aorta induced by endothelium-dependent agonists like acetylcholine or ADP. However, it was found ineffective toward vasodilation due to direct stimulation of smooth muscle cells by nitroglycerin.
Unit Definition One unit will cause a ΔA550 of 0.01 per min using N,N-dimethyl-p-phenylenediamine as substrate at pH 5.5 and 37 °C, in a 7 mL reaction volume.
Physical form Pale blue powder containing sodium chloride and sodium acetate

贮存方法

2-8°C密闭、阴凉干燥处

生态学数据

通常对水体是稍微有害的，不要将未稀释或大量产品接触地下水，水道或污水系统，未经政府许可勿将材料排入周围环境。